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mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption

Actin is highly enriched at dendritic spines, and actin remodeling plays an essential role in structural plasticity. The mammalian target of rapamycin complex 2 (mTORC2) is a regulator of actin polymerization. Here, we report that alcohol consumption increases F-actin content in the dorsomedial stri...

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Dettagli Bibliografici
Pubblicato in:Neuropsychopharmacology
Autori principali: Laguesse, Sophie, Morisot, Nadege, Phamluong, Khanhky, Sakhai, Samuel A., Ron, Dorit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983552/
https://ncbi.nlm.nih.gov/pubmed/29497165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0012-1
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