Histone deacetylases mediate GABA(A) receptor expression, physiology, and behavioral maladaptations in rat models of alcohol dependence

Alcohol use disorders are chronic debilitating diseases characterized by severe withdrawal symptoms that contribute to morbidity and relapse. GABA(A) receptor (GABA(A)R) adaptations have long been implicated in the chronic effects of alcohol and contribute to many withdrawal symptoms associated with...

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Publicat a:Neuropsychopharmacology
Autors principals: Bohnsack, John Peyton, Hughes, Benjamin A., O’Buckley, Todd K., Edokpolor, Kamyra, Besheer, Joyce, Morrow, A. Leslie
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983537/
https://ncbi.nlm.nih.gov/pubmed/29520058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0034-8
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