Histone deacetylases mediate GABA(A) receptor expression, physiology, and behavioral maladaptations in rat models of alcohol dependence

Alcohol use disorders are chronic debilitating diseases characterized by severe withdrawal symptoms that contribute to morbidity and relapse. GABA(A) receptor (GABA(A)R) adaptations have long been implicated in the chronic effects of alcohol and contribute to many withdrawal symptoms associated with...

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Publicado en:Neuropsychopharmacology
Main Authors: Bohnsack, John Peyton, Hughes, Benjamin A., O’Buckley, Todd K., Edokpolor, Kamyra, Besheer, Joyce, Morrow, A. Leslie
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983537/
https://ncbi.nlm.nih.gov/pubmed/29520058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0034-8
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