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Nrf2 and Keap1 abnormalities in esophageal squamous cell carcinoma and association with the effect of chemoradiotherapy

BACKGROUND: The Keap1‐Nrf2 pathway is a key antioxidant and redox signaling cascade. Pathway abnormalities enhance the reactive oxygen species scavenging ability of cancer cells; thus the pathway is involved in carcinogenesis and resistance to chemoradiotherapy (CRT). This retrospective study was co...

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Опубликовано в: :Thorac Cancer
Главные авторы: Zhang, Jingze, Jiao, Qinghua, Kong, Li, Yu, Jing, Fang, Aiju, Li, Minghuan, Yu, Jinming
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons Australia, Ltd 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983206/
https://ncbi.nlm.nih.gov/pubmed/29675925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12640
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