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Mutation in an alternative transcript of CDKL5 in a boy with early-onset seizures

Infantile-onset epilepsies are a set of severe, heterogeneous disorders for which clinical genetic testing yields causative mutations in ∼20%–50% of affected individuals. We report the case of a boy presenting with intractable seizures at 2 wk of age, for whom gene panel testing was unrevealing. Res...

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Vydáno v:Cold Spring Harb Mol Case Stud
Hlavní autoři: Bodian, Dale L., Schreiber, John M., Vilboux, Thierry, Khromykh, Alina, Hauser, Natalie S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983171/
https://ncbi.nlm.nih.gov/pubmed/29444904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a002360
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