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High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking

Uridine-rich small nuclear ribonucleoproteins (U snRNPs) are components of the splicing machinery that removes introns from precursor mRNA. Like other splicing factors, U snRNPs are diffusely distributed throughout the nucleus and, in addition, are concentrated in distinct nuclear substructures refe...

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Détails bibliographiques
Auteurs principaux: Kues, Thorsten, Dickmanns, Achim, Lührmann, Reinhard, Peters, Reiner, Kubitscheck, Ulrich
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC59825/
https://ncbi.nlm.nih.gov/pubmed/11593012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211250098
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