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Multiple roles of aryloxide leaving groups in enantioselective annulations employing α,β-unsaturated acyl ammonium catalysis

An isothiourea-catalysed Michael addition–annulation process using β-fluoroalkyl-substituted α,β-unsaturated aryl esters and a range of 2-acylbenzazoles is reported for the enantioselective synthesis of dihydropyranone and dihydropyridinone products bearing polyfluorinated stereocenters (29 examples...

詳細記述

保存先:
書誌詳細
出版年:Chem Sci
主要な著者: Greenhalgh, Mark D., Qu, Shen, Slawin, Alexandra M. Z., Smith, Andrew D.
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982221/
https://ncbi.nlm.nih.gov/pubmed/29910944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01324a
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