Roles of pyruvate dehydrogenase and branched-chain α-keto acid dehydrogenase in branched-chain membrane fatty acid levels and associated functions in Staphylococcus aureus

PURPOSE: Membrane fluidity to a large extent is governed by the presence of branched-chain fatty acids (BCFAs). Branched-chain α-keto acid dehydrogenase (BKD) is the key enzyme in BCFA synthesis. A Staphylococcus aureus BKD-deficient strain still produced substantial levels of BCFAs. Pyruvate dehydr...

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Detalhes bibliográficos
Publicado no:J Med Microbiol
Main Authors: Singh, Vineet K., Sirobhushanam, Sirisha, Ring, Robert P., Singh, Saumya, Gatto, Craig, Wilkinson, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982145/
https://ncbi.nlm.nih.gov/pubmed/29498620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jmm.0.000707
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