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BMPRIA is required for osteogenic differentiation and RANKL expression in adult bone marrow mesenchymal stromal cells
Bone morphogenetic proteins (BMPs) activate the canonical Smad1/5/8 and non-canonical Tak1-MAPK pathways via BMP receptors I and II to regulate skeletal development and bone remodeling. Specific ablation of Bmpr1a in immature osteoblasts, osteoblasts, or osteocytes results in an increase in cancello...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5981611/ https://ncbi.nlm.nih.gov/pubmed/29855498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26820-8 |
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