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Improvement of 2-Vessel Occlusion Cerebral Ischaemia/Reperfusion-Induced Corticostriatal Electrolyte and Redox Imbalance, Lactic Acidosis and Modified Acetylcholinesterase Activity by Kolaviron Correlates with Reduction in Neurobehavioural Deficits

BACKGROUND: Disruption of electrolyte, redox and neurochemical homeostasis alongside cellular energy crisis is a hallmark of cerebral ischaemia and reperfusion injury. PURPOSE: This study investigated the effect of kolaviron (KV) on cortical and striatal cation imbalance, oxidative stress and neuroc...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Neurosci
Hauptverfasser: Akinmoladun, Afolabi Clement, Saliu, Ibrahim Olabayode, Olowookere, Boyede Dele, Ojo, Olubukola Benedicta, Olaleye, Mary Tolulope, Farombi, Ebenezer Olatunde, Akindahunsi, Afolabi Akintunde
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981598/
https://ncbi.nlm.nih.gov/pubmed/29887685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000484517
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