Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882

Type II thioesterases typically function as editing enzymes, removing acyl groups that have been misconjugated to acyl carrier proteins during polyketide secondary metabolite biosynthesis as a consequence of biosynthetic errors. Streptomyces chartreusis NRRL 3882 produces the pyrrole polyether ionop...

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Vydáno v:Appl Environ Microbiol
Hlavní autoři: Wu, Hao, Liang, Jingdan, Gou, Lixia, Wu, Qiulin, Liang, Wei-Jun, Zhou, Xiufen, Bruce, Ian J., Deng, Zixin, Wang, Zhijun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Enzymology and Protein Engineering
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981075/
https://ncbi.nlm.nih.gov/pubmed/29654175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00587-18
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