Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882

Calcimycin, N-demethyl calcimycin, and cezomycin are polyether divalent cation ionophore secondary metabolites produced by Streptomyces chartreusis. A thorough understanding of the organization of their encoding genes, biosynthetic pathway(s), and cation specificities is vitally important for their...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Wu, Hao, Liang, Jingdan, Wang, Jialiang, Liang, Wei-Jun, Gou, Lixia, Wu, Qiulin, Zhou, Xiufen, Bruce, Ian J., Deng, Zixin, Wang, Zhijun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Enzymology and Protein Engineering
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981064/
https://ncbi.nlm.nih.gov/pubmed/29654174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00586-18
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