Short-Term Hemodynamic Effects of Apelin in Patients With Pulmonary Arterial Hypertension

Apelin agonism causes systemic vasodilatation and increased cardiac contractility in humans, and improves pulmonary arterial hypertension (PAH) in animal models. Here, the authors examined the short-term pulmonary hemodynamic effects of systemic apelin infusion in patients with PAH. In a double-blin...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Brash, Lauren, Barnes, Gareth D., Brewis, Melanie J., Church, A. Colin, Gibbs, Simon J., Howard, Luke S.G.E., Jayasekera, Geeshath, Johnson, Martin K., McGlinchey, Neil, Onorato, Joelle, Simpson, Joanne, Stirrat, Colin, Thomson, Stephen, Watson, Geoffrey, Wilkins, Martin R., Xu, Carrie, Welsh, David J., Newby, David E., Peacock, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
CLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981010/
https://ncbi.nlm.nih.gov/pubmed/29876530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.01.013
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