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Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies

The promyelocytic leukemia (pml) gene product PML is a tumor suppressor localized mainly in the nucleus of mammalian cells. In the cell nucleus, PML seeds the formation of macromolecular multiprotein complexes, known as PML nuclear bodies (PML NBs). While PML NBs have been implicated in many cellula...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Hoischen, Christian, Monajembashi, Shamci, Weisshart, Klaus, Hemmerich, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980967/
https://ncbi.nlm.nih.gov/pubmed/29888200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00125
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