Utility of 5-Methylcytosine Immunohistochemical Staining to Assess Global DNA Methylation and Its Prognostic Impact in MDS Patients

BACKGROUND: DNA methylation plays a vital role in the pathogenesis of the myelodysplastic syndrome (MDS), a heterogeneous group of clonal hematopoietic stem cell (HSC) disorders. It is reported to be an independent prognostic factor affecting overall survival (OS). Our aim was to analyze the role of...

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Detalles Bibliográficos
Publicado en:Asian Pac J Cancer Prev
Main Authors: Chandra, Dinesh, Tyagi, Seema, Singh, Jasdeep, Deka, Roopam, Manivannan, Prabhu, Mishra, Pravas, Pati, Hara Prasad, Saxena, Renu
Formato: Artigo
Idioma:Inglês
Publicado: West Asia Organization for Cancer Prevention 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980888/
https://ncbi.nlm.nih.gov/pubmed/29286224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2017.18.12.3307
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