A Germline Mutation in the BRCA1 3’UTR Variant Predicts Susceptibility to Breast Cancer in a Saudi Arabian Population

PURPOSE: The impact of the BRCA1-3’UTR-variant on BRCA1 gene expression and altered responses to external stimuli was previously tested in vitro using a luciferase reporter assay. Its ability to predict breast cancer risk in women was also assessed but the conclusions were inconsistent. The present...

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Udgivet i:Asian Pac J Cancer Prev
Main Authors: Mir, Rashid, Javid, Jamsheed, Al Balawi, Ibrahim Abdullah, Alkharsah, Khaled R., Hadi, Maha Abdel, Rahman, Mostafa Abdel, Hamoud, Ebtesam, Al Alawi, Yousef, Al Zahrani, Attiya Bin Mohammad, Abu-Duhier, FM
Format: Artigo
Sprog:Inglês
Udgivet: West Asia Organization for Cancer Prevention 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980867/
https://ncbi.nlm.nih.gov/pubmed/29582646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2018.19.3.859
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