Differences in the Serum 4β-hydroxycholesterol Levels of Patients with Chronic Hepatitis C Virus (HCV) Infection: A Possible Impact on the Efficacy and Safety of Interferon (IFN)-free Treatment

OBJECTIVE: Since the majority of direct-acting antivirals (DAAs) that are used in the treatment of hepatitis C virus (HCV) infection are mainly metabolized by CYP3A4, it is hypothesized that inter-individual differences in CYP3A4 activity may be associated with the bioavailability of these agents. M...

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Publicado en:Intern Med
Autores principales: Hirayama, Takeshi, Ikegami, Tadashi, Honda, Akira, Miyazaki, Teruo, Yara, Sho-Ichiro, Kohjima, Motoyuki, Nakamuta, Makoto, Matsuzaki, Yasushi
Formato: Artigo
Lenguaje:Inglês
Publicado: The Japanese Society of Internal Medicine 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980801/
https://ncbi.nlm.nih.gov/pubmed/29279486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.9479-17
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