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The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector

Ubiquitination is a post-translational modification that regulates a myriad of cellular processes in eukaryotes(1–4). The conventional ubiquitination cascade culminates in a covalent linkage between the C-terminus of ubiquitin (Ub) and a target protein, most often on a lysine sidechain(1,5). Recent...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Akturk, Anil, Wasilko, David J., Wu, Xiaochun, Liu, Yao, Zhang, Yong, Qiu, Jiazhang, Luo, Zhao-Qing, Reiter, Katherine H., Brzovic, Peter S., Klevit, Rachel E., Mao, Yuxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980775/
https://ncbi.nlm.nih.gov/pubmed/29795346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0147-6
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