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Association of Vibrio cholerae 569B outer membrane vesicles with host cells occurs in a GM1-independent manner

The primary virulence factor of Vibrio cholerae, cholera toxin (CT), initiates a pathway in epithelial cells that leads to the severe diarrhea characteristic of cholera. Secreted CT binds to GM1 on the surface of host cells to facilitate internalization. Many bacterial toxins, including CT, have bee...

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Библиографические подробности
Опубликовано в: :Cell Microbiol
Главные авторы: Rasti, Elnaz S., Schappert, Megan L., Brown, Angela C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980675/
https://ncbi.nlm.nih.gov/pubmed/29377560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12828
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