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Structural basis for tankyrase‐RNF146 interaction reveals noncanonical tankyrase‐binding motifs

Poly(ADP‐ribosyl)ation (PARylation) catalyzed by the tankyrase enzymes (Tankyrase‐1 and ‐2; a.k.a. PARP‐5a and ‐5b) is involved in mitosis, telomere length regulation, GLUT‐4 vesicle transport, and cell growth and differentiation. Together with the E3 ubiquitin ligase RNF146 (a.k.a. Iduna), tankyras...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: DaRosa, Paul A., Klevit, Rachel E., Xu, Wenqing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980575/
https://ncbi.nlm.nih.gov/pubmed/29604130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3413
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