Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N‐arachidonoylphosphatidylethanolamine

BACKGROUND AND PURPOSE: Endocannabinoids play an important role in modulating spinal nociceptive signalling, crucial for the development of pain. The cannabinoid CB(1) receptor and the TRPV1 cation channel are both activated by the endocannabinoid anandamide, a product of biosynthesis from the endog...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Nerandzic, Vladimir, Mrozkova, Petra, Adamek, Pavel, Spicarova, Diana, Nagy, Istvan, Palecek, Jiri
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Themed Section: Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980568/
https://ncbi.nlm.nih.gov/pubmed/28476070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13849
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