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Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine

BACKGROUND AND PURPOSE: Phenelzine is an antidepressant drug known to increase the risk of hypertensive crisis when dietary tyramine is not restricted. However, this MAO inhibitor inhibits other enzymes not limited to the nervous system. Here we investigated if its antiadipogenic and antilipogenic e...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Carpéné, Christian, Mercader, Josep, Le Gonidec, Sophie, Schaak, Stéphane, Mialet‐Perez, Jeanne, Zakaroff‐Girard, Alexia, Galitzky, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980542/
https://ncbi.nlm.nih.gov/pubmed/29582416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14211
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