Potential immune priming of the tumor microenvironment with FOLFOX chemotherapy in locally advanced rectal cancer

Strategies to enhance tumor immunogenicity may expand the role of immunotherapy beyond the mismatch repair-deficient subtype. In this pilot study, biopsies were performed at baseline and after four cycles of FOLFOX in eight patients receiving neoadjuvant chemotherapy for stage II/III locally advance...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Roxburgh, Campbell S., Shia, Jinru, Vakiani, Efsevia, Daniel, Tanisha, Weiser, Martin R.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980419/
https://ncbi.nlm.nih.gov/pubmed/29872576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1435227
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