Hispidulin suppresses cell growth and metastasis by targeting PIM1 through JAK2/STAT3 signaling in colorectal cancer

Colorectal cancer (CRC) accounts for over 600 000 deaths annually worldwide. The current study aims to evaluate the value of proto‐oncogene PIM1 as a therapeutic target in CRC and investigate the anticancer activity of hispidulin, a naturally occurring phenolic flavonoid compound, against CRC. Immun...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Liu, Kaili, Gao, Hui, Wang, Qiaoyun, Wang, Longyuan, Zhang, Bin, Han, Zhiwu, Chen, Xuehong, Han, Mei, Gao, Mingquan
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980372/
https://ncbi.nlm.nih.gov/pubmed/29575334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13575
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