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Heparanase attenuates axon degeneration following sciatic nerve transection

Axon degeneration underlies many nervous system diseases; therefore understanding the regulatory signalling pathways is fundamental to identifying potential therapeutics. Previously, we demonstrated heparan sulphates (HS) as a potentially new target for promoting CNS repair. HS modulate cell signall...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Whitehead, Michael J., McGonigal, Rhona, Willison, Hugh J., Barnett, Susan C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980233/
https://ncbi.nlm.nih.gov/pubmed/29581478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23070-6
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