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Exercise Mitigates Alcohol Induced Endoplasmic Reticulum Stress Mediated Cognitive Impairment through ATF6-Herp Signaling

Chronic ethanol/alcohol (AL) dosing causes an elevation in homocysteine (Hcy) levels, which leads to the condition known as Hyperhomocysteinemia (HHcy). HHcy enhances oxidative stress and blood-brain-barrier (BBB) disruption through modulation of endoplasmic reticulum (ER) stress; in part by epigene...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: George, Akash K., Behera, Jyotirmaya, Kelly, Kimberly E., Mondal, Nandan K., Richardson, Kennedy P., Tyagi, Neetu
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980102/
https://ncbi.nlm.nih.gov/pubmed/29581524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23568-z
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