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Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia

Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined. The Innate immune system can be activated by endogenous nucle...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Danilova, Nadia, Wilkes, Mark, Bibikova, Elena, Youn, Min-Young, Sakamoto, Kathleen M., Lin, Shuo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980095/
https://ncbi.nlm.nih.gov/pubmed/29581525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23561-6
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