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Engineered 3D vascular and neuronal networks in a microfluidic platform

Neurovascular coupling plays a key role in the pathogenesis of neurodegenerative disorders including motor neuron disease (MND). In vitro models provide an opportunity to understand the pathogenesis of MND, and offer the potential for drug screening. Here, we describe a new 3D microvascular and neur...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Osaki, Tatsuya, Sivathanu, Vivek, Kamm, Roger D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979969/
https://ncbi.nlm.nih.gov/pubmed/29581463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23512-1
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