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Adenovirus-mediated knockdown of activin A receptor type 2A attenuates immune-induced hepatic fibrosis in mice and inhibits interleukin-17-induced activation of primary hepatic stellate cells

Fibrosis induces a progressive loss of liver function, thus leading to organ failure. Activins are secreted proteins that belong to the transforming growth factor (TGF)-β superfamily, which initiate signaling by binding to their two type II receptors: Activin A receptor type 2A (ACVR2A) and activin...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Med
Main Authors: Zhang, Hongjun, Ju, Baoling, Nie, Ying, Song, Baohui, Xu, Yuanhong, Gao, Ping
פורמט: Artigo
שפה:Inglês
יצא לאור: D.A. Spandidos 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979935/
https://ncbi.nlm.nih.gov/pubmed/29620144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3600
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