Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1

We have recently found that diabetes-induced premature senescence of retinal endothelial cells is accompanied by NOX2-NADPH oxidase-induced increases in the ureohydrolase enzyme arginase 1 (A1). Here, we used genetic strategies to determine the specific involvement of A1 in diabetes-induced endothel...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Shosha, Esraa, Xu, Zhimin, Narayanan, S. Priya, Lemtalsi, Tahira, Fouda, Abdelrahman Y., Rojas, Modesto, Xing, Ji, Fulton, David, Caldwell, R. William, Caldwell, Ruth B.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979610/
https://ncbi.nlm.nih.gov/pubmed/29673160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041215
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