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Oncosuppressors and Oncogenes: Role in Haemangioma Genesis and Potential for Therapeutic Targeting

Genetic lesions in proto-oncogenes result in the perturbation of angiogenesis, the formation of neovessels from a pre-existing microvasculature. Similarly, the subversion of tumor suppressor genes promotes tumor vascularization. Excessive neovessel formation is associated with various neoplasms such...

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Bibliographic Details
Published in:Int J Mol Sci
Main Author: Mabeta, Peace
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979526/
https://ncbi.nlm.nih.gov/pubmed/29652858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041192
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