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Disruption of PTPS Gene Causing Pale Body Color and Lethal Phenotype in the Silkworm, Bombyx mori

Phenylketonuria (PKU) is an inborn error of metabolism caused by mutations in the phenylalanine hydroxylase (PAH) gene or by defects in the tetrahydrobiopterin (BH4) synthesis pathway. Here, by positional cloning, we report that the 6-pyruvoyl-tetrahydropterin synthase (PTPS) gene, encoding a key en...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Tong, Xiaoling, Liang, Pingfeng, Wu, Songyuan, Li, Yuanhao, Qiao, Liang, Hu, Hai, Xiang, Zhonghuai, Lu, Cheng, Dai, Fangyin
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979516/
https://ncbi.nlm.nih.gov/pubmed/29596327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041024
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