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Novel (1E,3E,5E)-1,6-bis(Substituted phenyl)hexa-1,3,5-triene Analogs Inhibit Melanogenesis in B16F10 Cells and Zebrafish

The present study aimed to evaluate the anti-melanogenic activity of 1,6-diphenyl-1,3,5-hexatriene and its derivatives in B16F10 murine melanoma cells and zebrafish embryos. Twenty five (1E,3E,5E)-1,6-bis(substituted phenyl)hexa-1,3,5-triene analogs were synthesized and their non-cytotoxic effects w...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Oh, Jisun, Kim, Jungeun, Jang, Jin Ho, Lee, Sangwoo, Park, Chul Min, Kim, Woo-Keun, Kim, Jong-Sang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979499/
https://ncbi.nlm.nih.gov/pubmed/29614034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041067
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