Dabrafenib Treatment in a Patient with an Epithelioid Glioblastoma and BRAF V600E Mutation

Novel therapeutic targets in malignant glioma patients are urgently needed. Point mutations of the v-Raf murine sarcoma viral oncogene homolog B (BRAF) gene occur predominantly in melanoma patients, but may also occur in gliomas. Thus, this is a target of great interest for this group of patients. I...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Ceccon, Garry, Werner, Jan-Michael, Dunkl, Veronika, Tscherpel, Caroline, Stoffels, Gabriele, Brunn, Anna, Deckert, Martina, Fink, Gereon R., Galldiks, Norbert
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Case Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979405/
https://ncbi.nlm.nih.gov/pubmed/29621181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041090
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