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Resistance to Anti-Angiogenic Therapy in Cancer—Alterations to Anti-VEGF Pathway

Anti-angiogenic therapy is one of the promising strategies for many types of solid cancers. Bevacizumab (Avastin), a recombinant humanized monoclonal antibody of vascular endothelial growth factor (VEGF) A, was approved for the first time as an anti-angiogenic drug for the treatment of metastatic co...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Itatani, Yoshiro, Kawada, Kenji, Yamamoto, Takamasa, Sakai, Yoshiharu
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979390/
https://ncbi.nlm.nih.gov/pubmed/29670046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041232
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