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Erythropoietin Intensifies the Proapoptotic Activity of LFM-A13 in Cells and in a Mouse Model of Colorectal Cancer

The Bruton’s tyrosine kinase (BTK) inhibitor LFM-A13 has been widely employed as an antileukemic agent, but applications in solid cancer have been found recently. The compound promotes apoptosis, has an antiproliferative effect, and increases cancer cell sensitivity to chemotherapy drugs. We decided...

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Publicat a:Int J Mol Sci
Autors principals: Tankiewicz-Kwedlo, Anna, Hermanowicz, Justyna Magdalena, Pawlak, Krystyna, Czarnomysy, Robert, Bielawski, Krzysztof, Prokop, Izabela, Pawlak, Dariusz
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979332/
https://ncbi.nlm.nih.gov/pubmed/29690619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041262
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