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Brca1 Is Upregulated by 5-Aza-CdR and Promotes DNA Repair and Cell Survival, and Inhibits Neurite Outgrowth in Rat Retinal Neurons

Previous studies have reported that Brca1 acts as a “hinge” in the development of the central nervous system (CNS). However, the precise role of Brca1 in rat retinal neurons remains unclear. Here, we found that Brca1 is developmentally downregulated and silenced in adult retina. Brca1 was upregulate...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Qiyun, Xu, Lijun, Chen, Pei, Xu, Zhuojun, Qiu, Jin, Ge, Jian, Yu, Keming, Zhuang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979323/
https://ncbi.nlm.nih.gov/pubmed/29673145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041214
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