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An SCF(FBXO28) E3 Ligase Protects Pancreatic β-Cells from Apoptosis

Loss of pancreatic β-cell function and/or mass is a central hallmark of all forms of diabetes but its molecular basis is incompletely understood. β-cell apoptosis contributes to the reduced β-cell mass in diabetes. Therefore, the identification of important signaling molecules that promote β-cell su...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gorrepati, Kanaka Durga Devi, He, Wei, Lupse, Blaz, Yuan, Ting, Maedler, Kathrin, Ardestani, Amin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979299/
https://ncbi.nlm.nih.gov/pubmed/29587369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040975
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