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Gene target selection for loop-mediated isothermal amplification for rapid discrimination of Treponema pallidum subspecies

We show proof of concept for gene targets (polA, tprL, and TP_0619) that can be used in loop-mediated isothermal amplification (LAMP) assays to rapidly differentiate infection with any of the three Treponema pallidum subspecies (pallidum (TPA), pertenue (TPE), and endemicum (TEN)) and which are know...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Knauf, Sascha, Lüert, Simone, Šmajs, David, Strouhal, Michal, Chuma, Idrissa S., Frischmann, Sieghard, Bakheit, Mohammed
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5978989/
https://ncbi.nlm.nih.gov/pubmed/29649256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006396
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