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Balancing tonic and phasic inhibition in hypothalamic corticotropin‐releasing hormone neurons

KEY POINTS: GABA transporter (GAT) blockade recruits extrasynaptic GABA(A) receptors (GABA(A)Rs) and amplifies constitutive presynaptic GABA(B)R activity. Extrasynaptic GABA(A)Rs contribute to a tonic current. Corticosteroids increase the tonic current mediated by extrasynaptic GABA(A)Rs. ABSTRACT:...

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Pubblicato in:J Physiol
Autori principali: Colmers, Phillip L.W., Bains, Jaideep S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5978301/
https://ncbi.nlm.nih.gov/pubmed/29419884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275588
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