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Anti‐cancer therapy: senescence is the new black

Cellular senescence is a natural safeguard against cancer. Pharmacologically, it can be induced by drugs that inhibit the CDK4/6 kinases such as palbociclib, but the exact mechanism has never been dissected. Recent research by Miettinen et al (2018) reveals that senescence induced by this class of d...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Leite de Oliveira, Rodrigo, Bernards, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5978283/
https://ncbi.nlm.nih.gov/pubmed/29669859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899386
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