Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions—benign adenomas and inflammatory bowel disease

BACKGROUND: Active demethylation of 5-methyl-2′-deoxycytidine (5-mdC) in DNA occurs by oxidation to 5-(hydroxymethyl)-2′-deoxycytidine (5-hmdC) and further oxidation to 5-formyl-2′-deoxycytidine (5-fdC) and 5-carboxy-2′-deoxycytidine (5-cadC), and is carried out by enzymes of the ten-eleven transloc...

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Detalles Bibliográficos
Publicado en:Clin Epigenetics
Main Authors: Dziaman, Tomasz, Gackowski, Daniel, Guz, Jolanta, Linowiecka, Kinga, Bodnar, Magdalena, Starczak, Marta, Zarakowska, Ewelina, Modrzejewska, Martyna, Szpila, Anna, Szpotan, Justyna, Gawronski, Maciej, Labejszo, Anna, Liebert, Ariel, Banaszkiewicz, Zbigniew, Klopocka, Maria, Foksinski, Marek, Marszalek, Andrzej, Olinski, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977551/
https://ncbi.nlm.nih.gov/pubmed/29875879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0505-0
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