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Impact of the biological definition of Alzheimer’s disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology?

BACKGROUND: The NIA-AA research framework proposes a biological definition of Alzheimer’s disease, where asymptomatic persons with amyloid deposition would be considered as having this disease prior to symptoms. DISCUSSION: Notwithstanding the fact that amyloid deposition in isolation is not associa...

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Podrobná bibliografie
Vydáno v:Transl Neurodegener
Hlavní autoři: Gauthier, S., Zhang, H., Ng, K. P., Pascoal, T.A., Rosa-Neto, P.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977549/
https://ncbi.nlm.nih.gov/pubmed/29876101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-018-0117-9
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