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Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers

BACKGROUND: Hepatocellular carcinoma (HCC) is the one of the most common cancers and lethal diseases in the world. DNA methylation alteration is frequently observed in HCC and may play important roles in carcinogenesis and diagnosis. METHODS: Using the TCGA HCC dataset, we classified HCC patients in...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Cheng, Jinming, Wei, Dongkai, Ji, Yuan, Chen, Lingli, Yang, Liguang, Li, Guang, Wu, Leilei, Hou, Ting, Xie, Lu, Ding, Guohui, Li, Hong, Li, Yixue
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977535/
https://ncbi.nlm.nih.gov/pubmed/29848370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0548-z
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