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Methylphosphate Cap Structure in Small RNAs Reduces the Affinity of RNAs to La Protein

La protein is an abundant 47-kDa phosphoprotein found mostly in the nucleus of eukaryotic cells with a small fraction present in the cytoplasm. Nascent RNA transcripts synthesized by RNA polymerase III are known to be associated with La protein. This binding has been shown to occur to the 3′ end of...

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Bibliografische gegevens
Gepubliceerd in:Gene Expr
Hoofdauteurs: Bhattacharya, Rajat, Perumal, Karthika, Sinha, Krishna, Maraia, Richard, Reddy, Ram
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cognizant Communication Corporation 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977522/
https://ncbi.nlm.nih.gov/pubmed/12450216
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