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Methylphosphate Cap Structure in Small RNAs Reduces the Affinity of RNAs to La Protein

La protein is an abundant 47-kDa phosphoprotein found mostly in the nucleus of eukaryotic cells with a small fraction present in the cytoplasm. Nascent RNA transcripts synthesized by RNA polymerase III are known to be associated with La protein. This binding has been shown to occur to the 3′ end of...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Bhattacharya, Rajat, Perumal, Karthika, Sinha, Krishna, Maraia, Richard, Reddy, Ram
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977522/
https://ncbi.nlm.nih.gov/pubmed/12450216
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