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DICER1 Syndrome: DICER1 Mutations in Rare Cancers

DICER1 syndrome is a rare genetic disorder that predisposes individuals to multiple cancer types. Through mutations of the gene encoding the endoribonuclease, Dicer, DICER1 syndrome disrupts the biogenesis and processing of miRNAs with subsequent disruption in control of gene expression. Since the f...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Robertson, Jake C., Jorcyk, Cheryl L., Oxford, Julia Thom
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977116/
https://ncbi.nlm.nih.gov/pubmed/29762508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10050143
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