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The Utility of Next-Generation Sequencing for Primary Immunodeficiency Disorders: Experience from a Clinical Diagnostic Laboratory

INTRODUCTION: Primary immune deficiency disorders (PIDs) are a group of diseases with profound defects in immune cells. The traditional diagnostics have evolved from clinical evaluation, flow cytometry, western blotting, and Sanger sequencing to focusing on small groups of genes. However, this is no...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Bisgin, Atil, Boga, Ibrahim, Yilmaz, Mustafa, Bingol, Gulbin, Altintas, Derya
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977064/
https://ncbi.nlm.nih.gov/pubmed/29888287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9647253
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