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Epstein Barr Virus Infection Affects Function of Cytotoxic T Lymphocytes in Patients with Severe Aplastic Anemia

Severe aplastic anemia (SAA) is characterized by pancytopenia and failure of hematopoietic function and is caused by excessive functioning of cytotoxic T lymphocytes (CTLs). EBNA-1, a nucleoprotein of the Epstein Barr virus (EBV), can influence the proliferation and function of lymphocytes. We there...

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Détails bibliographiques
Publié dans:Biomed Res Int
Auteurs principaux: Zhang, Tian, Liu, Chunyan, Liu, Hui, Li, Lijuan, Wang, Ting, Fu, Rong
Format: Artigo
Langue:Inglês
Publié: Hindawi 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976969/
https://ncbi.nlm.nih.gov/pubmed/29862282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6413815
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