First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [(11)C]SAR127303

Monoacylglycerol lipase (MAGL) is a main regulator of the endocannabinoid system within the central nervous system (CNS). Recently, [(11)C]SAR127303 was developed as a promising radioligand for MAGL imaging. In this study, we aimed to quantify regional MAGL concentrations in the rat brain using posi...

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Bibliografske podrobnosti
izdano v:Neuroimage
Main Authors: Yamasaki, Tomoteru, Mori, Wakana, Zhang, Yiding, Hatori, Akiko, Fujinaga, Masayuki, Wakizaka, Hidekatsu, Kurihara, Yusuke, Wang, Lu, Nengaki, Nobuki, Ohya, Tomoyuki, Liang, Steven H., Zhang, Ming-Rong
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976552/
https://ncbi.nlm.nih.gov/pubmed/29738910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2018.05.015
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