Continued tumor reduction of metastatic pheochromocytoma/paraganglioma harboring succinate dehydrogenase subunit B mutations with cyclical chemotherapy

Patients harboring germline mutations in the succinate dehydrogenase complex subunit B (SDHB) gene present with pheochromocytomas and paragangliomas (PPGL) that are more likely malignant and clinically aggressive. The combination chemotherapy cyclophosphamide, vincristine, and dacarbazine (CVD) was...

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Veröffentlicht in:Cell Mol Neurobiol
Hauptverfasser: Jawed, Irfan, Velarde, Margarita, Därr, Roland, Wolf, Katherine I., Adams, Karen, Venkatesan, Aradhana M., Balasubramaniam, Sanjeeve, Poruchynsky, Marianne S., Reynolds, James C., Pacak, Karel, Fojo, Tito
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976545/
https://ncbi.nlm.nih.gov/pubmed/29623478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-018-0579-4
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