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PSA-selective activation of cytotoxic human serine proteases within the tumor microenvironment as a therapeutic strategy to target prostate cancer

Prostate cancer is the most diagnosed malignancy and the second leading cause of cancer-related death in American men. While localized therapy is highly curative, treatments for metastatic prostate cancer are largely palliative. Thus, new innovative therapies are needed to target metastatic tumors....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rogers, Oliver C., Anthony, Lizamma, Rosen, D. Marc, Brennen, W. Nathaniel, Denmeade, Samuel R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976476/
https://ncbi.nlm.nih.gov/pubmed/29854290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25091
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